As  we  grapple  with  climate  change  and  myriad  ecological  crises, conceptual tools from other disciplines offer opportunities for new analytical frameworks. This introduction brings a multispecies anthropological approach into dialogue with biological  understandings  of  the  relationships  involved  in  domestication. It examines  mutualism  as  a  series  of  interspecies  social  interactions  that,  despite  some  costs,  benefit  each partner species on balance.